KMID : 1161420110140010108
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Journal of Medicinal Food 2011 Volume.14 No. 1 p.108 ~ p.113
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Supplementation of Cheonggukjang and Red Ginseng Cheonggukjang Can Improve Plasma Lipid Profile and Fasting Blood Glucose Concentration in Subjects with Impaired Fasting Glucose
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Shin Su-Kyung
Kwon Joong-Hoo Jeong Yong-Jin Jeon Seon-Min Choi Ji-Young Choi Myung-Sook
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Abstract
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This study was conducted to investigate the plasma lipid profile and blood glucose-lowering effects of cheonggukjang (CH) and red ginseng CH (RGCH) in 45 subjects (men:women?=?27:18; mean age, 44.9?¡¾?3.1 years) with impaired fasting glucose (IFG). Subjects were randomly divided into three groups: control (starch, 2?g/day), CH (20?g/day), and RGCH (20?g/day). Each volunteer received his or her daily doses for 8 weeks. The supplementation with CH and RGCH significantly decreased the plasma total cholesterol about 30.0?mg/mL and 37.7?mg/mL, respectively, compared to the initial value. The plasma low-density lipoprotein-cholesterol concentration was also significantly reduced by 29.66% and 23.42% in the CH and RGCH groups, respectively, compared to the initial value. The concentration of plasma non?high-density lipoprotein-cholesterol (107.9?mg/mL) was significantly lowered in the RGCH group compared to the initial value (139.1?mg/mL). The level of erythrocyte thiobarbituric acid-reactive substances was significantly lowered in the CH (6.5?nmol/mL) and RGCH (6.6?nmol/mL) groups compared to the initial value (7.9?nmol/mL and 8.0?nmol/mL, respectively). The ratio of apolipoprotein B and apolipoprotein A-1 concentrations (2.5) was significantly reduced in the CH group compared to the initial value (3.0). The concentration of fasting blood glucose (FBG) was significantly lower in the CH- and RGCH-supplemented groups compared to the initial value. These results suggest that CH and RGCH can lower the FBG concentration and improve the plasma lipid profile in subjects with IFG.
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KEYWORD
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fermented foods, human, lipids
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